The "exclusive" variant of this error usually points to one of three things:
A previous analysis crashed, but the solver process is still "holding" the project files.
Verify that ports and 27000-27009 (default FlexLM ports) are open. Prevention Tips
Always keep your .sdy files on your local hard drive during the analysis. Move them to the server only after the solve is complete.
Ensure you are running the latest version of the Simulation Job Manager, as Autodesk frequently releases patches for these communication errors.
Don't try to run an analysis on a project file that is currently open in another instance of Moldflow.
Troubleshooting Autodesk Moldflow Error 99998: Solving the Exclusive Lock Issue