The job isn't done just because you see the desktop. To make your Hackintosh a daily driver, you need to handle "Post-Install":
Hackintosh Zone (Niresh) is popular because it provides "distros"—modified installers that include various drivers (Kexts) and bootloaders out of the box. Step 1: Preparation hackintosh zone catalina
You will likely see the Clover or OpenCore menu. Select "Boot macOS Install from [USB Name]." The job isn't done just because you see the desktop
Most RX 400, 500, Vega, and 5000-series cards are "plug and play." hackintosh zone catalina
Do you have a specific model you’re planning to use so we can check for known compatibility issues?