Led by Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, and others.
The (2025/2026), continues its legacy as the "most recognized book in all of medicine" . This latest edition represents a significant structural overhaul designed for modern clinical reasoning. While the English edition was released in July 2025 , the Spanish language version— Principios de Medicina Interna —is becoming available through major medical platforms and retailers globally. Overview of the 22nd Edition
Available in a massive two-volume print set (approx. 4,400+ pages) and as a comprehensive digital resource. New Features and Updates
The 22nd edition is more than a simple update; it includes a standardized format for disease chapters to improve readability and clinical utility. Harrison's Principles of Internal Medicine, 22nd Edition
The English version was published in July 2025. The Spanish edition and comprehensive online access launched shortly after, with some regional physical distributions scheduled through May 2026.
