Neovaginas created from penile/scrotal skin flaps or intestinal tissue do not have a cervix. Therefore, standard cervical cancer screenings (Pap smears) are unnecessary.
Swabs of the rectum and pharynx are critical depending on individual sexual practices. Transgender Women With Vaginoplasty (Neovagina) Ladyboy Sex Diseases
The worldwide burden of HIV in transgender individuals - PMC Ladyboy Sex Diseases